Fanconi anaemia is an inherited disorder with greatly elevated risk of leukaemia and cancers. A causal gene called FANCM is a ‘tumour suppressor’. Our work is uncovering its tumour suppressor function: a complex function in repair of damage to our DNA. This study aims to understand how this protects us from cancer, and may influence some forms of cancer treatment.
https://www.svi.edu.au/research_themes/genome_stability: The role of FANCM, a gene mutated in Fanconi Anaemia